A convenient alternative to harden bone filling materials are injectable bone substitutes ibs in this article recent progress in the development and application of calcium phosphate cp based composites use as ibs is reviewed cp materials have been used widely for bone replacement because of their similarity to the mineral component of bone. Calcium phosphate materials bone substitution 9780412494208 books amazonca skip to main contentca hello select your address books hello sign in account lists account returns orders cart all gift cards best sellers gift ideas . Hydroxyapatite or tricalcium phosphate are used as bone substitutes however their mechanical strength is insufficient for weight bearing and they are used as bone filler. The aim of this study was to determine the material composition and cell mediated remodelling of different calcium phosphate based bone substitutes osteoclasts were cultivated on bone substitutes cerabone maxresorb and nanobone for up to 5 days bafilomycin a1 addition served as the control to determine cellular activity the supernatant content of calcium and phosphate was measured by