The continuing nemesis of experimenting with sea drugs is supply getting enough material to test let alone produce a drug in the case of eleutherobin researchers got lucky in 1997 a group headed by chemist k c nicolaou at the scripps research institute managed to make the drug in the lab using cheap starting materials cardamom and dill. Looking at drugs from nature it is surprising that up to now almost all medicinally used natural products or derivatives thereof were obtained from terrestrial organisms rather than from those inhabiting the sea the oceans cover more than 70 of the earthsurface and are an indispensable source of protein for human nutrition. The algae eating indian sea hare dolabella auricularia is the source of dolastatin the basis for the drug auristatinstudies of this drug show benefits for the treatment of non small cell lung . Drugs already based upon compounds in this sponge include the aids drug azt an anti viral drug called ara a and the anti leukemia drug ara c the algae eating indian sea hare dolabella auricularia is the source of dolastatin the basis for the drug auristatin
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